- Rogers Lab -

2021

Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases
M. Wiedmann, P. K. Dranchak, M. Aitha, B. Queme, C. D. Collmus, M. M. Kashipathy, L. Kanter, L. Lamy, J. M. Rogers, D. Tao, K. P. Battaile, G. Rai, S. Lovell, H. Suga, and J. Inglese. J Biol Chem, (Advance Article), 2021. doi:10.1016/j.jbc.2021.100628
In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides
J. M. Rogers, M. Nawatha, B. Lemma, G. B. Vamisetti, I. Livneh, U. Barash, I. Vlodavsky, A. Ciechanover, D. Fushman, H. Suga & A. Brik. RSC Chem Biol, 2, 513-522, 2021. doi:10.1039/d0cb00179a

2020

Peptide Folding and Binding Probed by Systematic Non-canonical Mutagenesis
J. M. Rogers. Front Mol Biosci , 7, 100, 2020. doi:10.3389/fmolb.2020.00100

Initiating ribosomal peptide synthesis with exotic building blocks
C. Tsiamantas, J. M. Rogers, and H. Suga. Chem Commun, 56(31):4265–4272, 2020. doi:10.1039/d0cc01291b.

@article{RN205,
    author = "Tsiamantas, C. and J. M. Rogers and Suga, H.",
    title = "Initiating ribosomal peptide synthesis with exotic building blocks",
    journal = "Chem Commun",
    volume = "56",
    number = "31",
    pages = "4265-4272",
    DOI = "10.1039/d0cc01291b",
    year = "2020"
}

Ribosomal incorporation of aromatic oligoamides as peptide side-chain appendages
C. Tsiamantas, S. Kwon, J. M. Rogers, C. Douat, I. Huc, and H. Suga. Angew Chem Int Ed Engl, 2020. doi:10.1002/anie.201914654.

@article{RN159,
    author = "Tsiamantas, C. and Kwon, S. and J. M. Rogers and Douat, C. and Huc, I. and Suga, H.",
    title = "Ribosomal incorporation of aromatic oligoamides as peptide side-chain appendages",
    journal = "Angew Chem Int Ed Engl",
    DOI = "10.1002/anie.201914654",
    year = "2020"
}

Affinity maturation of macrocyclic peptide modulators of lys48-linked diubiquitin by a twofold strategy
Y. Huang, M. Nawatha, I. Livneh, J. M. Rogers, H. Sun, S. K. Singh, A. Ciechanover, A. Brik, and H. Suga. Chem Eur, 2020. doi:10.1002/chem.202000273.

@article{RN199,
    author = "Huang, Y. and Nawatha, M. and Livneh, I. and J. M. Rogers and Sun, H. and Singh, S. K. and Ciechanover, A. and Brik, A. and Suga, H.",
    title = "Affinity Maturation of Macrocyclic Peptide Modulators of Lys48-linked Diubiquitin by a Twofold Strategy",
    journal = "Chem Eur",
    DOI = "10.1002/chem.202000273",
    year = "2020"
}

2019

De novo macrocyclic peptides that specifically modulate lys48-linked ubiquitin chains
M. Nawatha, J. M. Rogers, S. M. Bonn, I. Livneh, B. Lemma, S. M. Mali, G. B. Vamisetti, H. Sun, B. Bercovich, Y. Huang, A. Ciechanover, D. Fushman, H. Suga, and A. Brik. Nat Chem, 11(7):644–652, 2019. doi:10.1038/s41557-019-0278-x.

@article{RN160,
    author = "Nawatha, M. and J. M. Rogers and Bonn, S. M. and Livneh, I. and Lemma, B. and Mali, S. M. and Vamisetti, G. B. and Sun, H. and Bercovich, B. and Huang, Y. and Ciechanover, A. and Fushman, D. and Suga, H. and Brik, A.",
    title = "De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains",
    journal = "Nat Chem",
    volume = "11",
    number = "7",
    pages = "644-652",
    DOI = "10.1038/s41557-019-0278-x",
    year = "2019"
}

2018

Nonproteinogenic deep mutational scanning of linear and cyclic peptides
J. M. Rogers, T. Passioura, and H. Suga. Proc Natl Acad Sci U S A, 115(43):10959–10964, 2018. doi:10.1073/pnas.1809901115.

@article{RN161,
    author = "J. M. Rogers and Passioura, T. and Suga, H.",
    title = "Nonproteinogenic deep mutational scanning of linear and cyclic peptides",
    journal = "Proc Natl Acad Sci U S A",
    volume = "115",
    number = "43",
    pages = "10959-10964",
    DOI = "10.1073/pnas.1809901115",
    year = "2018"
}

Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids
J. M. Rogers, S. Kwon, S. J. Dawson, P. K. Mandal, H. Suga, and I. Huc. Nat Chem, 10(4):405–412, 2018. doi:10.1038/s41557-018-0007-x.

@article{RN162,
    author = "J. M. Rogers and Kwon, S. and Dawson, S. J. and Mandal, P. K. and Suga, H. and Huc, I.",
    title = "Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids",
    journal = "Nat Chem",
    volume = "10",
    number = "4",
    pages = "405-412",
    DOI = "10.1038/s41557-018-0007-x",
    year = "2018"
}

2015

Discovering functional, non-proteinogenic amino acid containing, peptides using genetic code reprogramming
J. M. Rogers and H. Suga. Org Biomol Chem, 13(36):9353–63, 2015. doi:10.1039/c5ob01336d.

@article{RN164,
    author = "J. M. Rogers and Suga, H.",
    title = "Discovering functional, non-proteinogenic amino acid containing, peptides using genetic code reprogramming",
    journal = "Org Biomol Chem",
    volume = "13",
    number = "36",
    pages = "9353-63",
    DOI = "10.1039/c5ob01336d",
    year = "2015"
}

Model foldamers: applications and structures of stable macrocyclic peptides identified using in vitro selection
S. A. K. Jongkees, C. J. Hipolito, J. M. Rogers, and H. Suga. New J Chem, 2015. doi:10.1039/c4nj01633e.

@article{RN165,
    author = "Jongkees, S. A. K. and Hipolito, C. J. and J. M. Rogers and Suga, H.",
    title = "Model foldamers: applications and structures of stable macrocyclic peptides identified using in vitro selection",
    journal = "New J Chem",
    DOI = "10.1039/c4nj01633e",
    year = "2015"
}

2014

Coupled folding and binding of the disordered protein PUMA does not require particular residual structure
J. M. Rogers, C. T. Wong, and J. Clarke. J Am Chem Soc, 136(14):5197–200, 2014. doi:10.1021/ja4125065.

@article{RN166,
    author = "J. M. Rogers and Wong, C. T. and Clarke, J.",
    title = "Coupled folding and binding of the disordered protein PUMA does not require particular residual structure",
    journal = "J Am Chem Soc",
    volume = "136",
    number = "14",
    pages = "5197-200",
    DOI = "10.1021/ja4125065",
    year = "2014"
}

Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein
J. M. Rogers, V. Oleinikovas, S. L. Shammas, C. T. Wong, D. De Sancho, C. M. Baker, and J. Clarke. Proc Natl Acad Sci U S A, 111(43):15420–15425, 2014. doi:Doi 10.1073/Pnas.1409122111.

@article{RN167,
    author = "J. M. Rogers and Oleinikovas, V. and Shammas, S. L. and Wong, C. T. and De Sancho, D. and Baker, C. M. and Clarke, J.",
    title = "Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein",
    journal = "Proc Natl Acad Sci U S A",
    volume = "111",
    number = "43",
    pages = "15420-15425",
    DOI = "Doi 10.1073/Pnas.1409122111",
    year = "2014"
}

High thermodynamic stability of parametrically designed helical bundles
P. S. Huang, G. Oberdorfer, C. Xu, X. Y. Pei, B. L. Nannenga, J. M. Rogers, F. DiMaio, T. Gonen, B. Luisi, and D. Baker. Science, 346(6208):481–5, 2014. doi:10.1126/science.1257481.

@article{RN168,
    author = "Huang, P. S. and Oberdorfer, G. and Xu, C. and Pei, X. Y. and Nannenga, B. L. and J. M. Rogers and DiMaio, F. and Gonen, T. and Luisi, B. and Baker, D.",
    title = "High thermodynamic stability of parametrically designed helical bundles",
    journal = "Science",
    volume = "346",
    number = "6208",
    pages = "481-5",
    DOI = "10.1126/science.1257481",
    year = "2014"
}

2013

Folding and binding of an intrinsically disordered protein: fast, but not 'diffusion-limited'
J. M. Rogers, A. Steward, and J. Clarke. J Am Chem Soc, 135(4):1415–22, 2013. doi:10.1021/ja309527h.

@article{RN169,
    author = "J. M. Rogers and Steward, A. and Clarke, J.",
    title = "Folding and binding of an intrinsically disordered protein: fast, but not 'diffusion-limited'",
    journal = "J Am Chem Soc",
    volume = "135",
    number = "4",
    pages = "1415-22",
    DOI = "10.1021/ja309527h",
    year = "2013"
}

2012

Protein folding: adding a nucleus to guide helix docking reduces landscape roughness
B. G. Wensley, L. G. Kwa, S. L. Shammas, J. M. Rogers, and J. Clarke. J Mol Biol, 423(3):273–83, 2012. doi:10.1016/j.jmb.2012.08.003.

@article{RN170,
    author = "Wensley, B. G. and Kwa, L. G. and Shammas, S. L. and J. M. Rogers and Clarke, J.",
    title = "Protein folding: adding a nucleus to guide helix docking reduces landscape roughness",
    journal = "J Mol Biol",
    volume = "423",
    number = "3",
    pages = "273-83",
    DOI = "10.1016/j.jmb.2012.08.003",
    year = "2012"
}

Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains
B. G. Wensley, L. G. Kwa, S. L. Shammas, J. M. Rogers, S. Browning, Z. Yang, and J. Clarke. Proc Natl Acad Sci U S A, 109(44):17795–9, 2012. doi:10.1073/pnas.1201793109.

@article{RN171,
    author = "Wensley, B. G. and Kwa, L. G. and Shammas, S. L. and J. M. Rogers and Browning, S. and Yang, Z. and Clarke, J.",
    title = "Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains",
    journal = "Proc Natl Acad Sci U S A",
    volume = "109",
    number = "44",
    pages = "17795-9",
    DOI = "10.1073/pnas.1201793109",
    year = "2012"
}

Two immunoglobulin tandem proteins with a linking beta-strand reveal unexpected differences in cooperativity and folding pathways
A. Steward, Q. Chen, R. I. Chapman, M. B. Borgia, J. M. Rogers, A. Wojtala, M. Wilmanns, and J. Clarke. J Mol Biol, 416(1):137–47, 2012. doi:10.1016/j.jmb.2011.12.012.

@article{RN172,
    author = "Steward, A. and Chen, Q. and Chapman, R. I. and Borgia, M. B. and J. M. Rogers and Wojtala, A. and Wilmanns, M. and Clarke, J.",
    title = "Two immunoglobulin tandem proteins with a linking beta-strand reveal unexpected differences in cooperativity and folding pathways",
    journal = "J Mol Biol",
    volume = "416",
    number = "1",
    pages = "137-47",
    DOI = "10.1016/j.jmb.2011.12.012",
    year = "2012"
}

Slow, reversible, coupled folding and binding of the spectrin tetramerization domain
S. L. Shammas, J. M. Rogers, S. A. Hill, and J. Clarke. Biophys J, 103(10):2203–14, 2012. doi:10.1016/j.bpj.2012.10.012.

@article{RN173,
    author = "Shammas, S. L. and J. M. Rogers and Hill, S. A. and Clarke, J.",
    title = "Slow, reversible, coupled folding and binding of the spectrin tetramerization domain",
    journal = "Biophys J",
    volume = "103",
    number = "10",
    pages = "2203-14",
    DOI = "10.1016/j.bpj.2012.10.012",
    year = "2012"
}

2010

Experimental detection of knotted conformations in denatured proteins
A. L. Mallam, J. M. Rogers, and S. E. Jackson. Proc Natl Acad Sci U S A, 107(18):8189–94, 2010. doi:10.1073/pnas.0912161107.

@article{RN174,
    author = "Mallam, A. L. and J. M. Rogers and Jackson, S. E.",
    title = "Experimental detection of knotted conformations in denatured proteins",
    journal = "Proc Natl Acad Sci U S A",
    volume = "107",
    number = "18",
    pages = "8189-94",
    DOI = "10.1073/pnas.0912161107",
    year = "2010"
}